Asthma Research Is In The Air
The FLAIR Study is evaluating an investigational drug for children and adults with asthma.
About the Study
The FLAIR Study is evaluating an investigational drug to see how it works in reducing the severity and frequency of “asthma attacks”.
See if Your Child Qualifies
If your child is 4 years old or older and has been diagnosed with asthma for at least 1 year, they may qualify for the FLAIR Study.
About the Study
See if Your Child Qualifies
If your child is 4 years of age or older and has been diagnosed with asthma for at least 1 year, they may qualify for the FLAIR Study.
See if You Qualify
Who can participate in the FLAIR Study?
The FLAIR Study is evaluating an investigational drug to see how it works in reducing the severity and frequency of “asthma attacks” in children and adults.
To participate in this study, you or your child must:
Be 4 years of age or older
Be diagnosed with asthma for at least 1 year
Had 1 or more asthma attacks in the past 12 months that was considered severe or required treatment
Adults over the age of 18 must not be current smokers or have a history of heavy smoking
There are also other requirements that will determine who can participate. A doctor will determine if you or your child is medically eligible to take part in this study.
See if You or Your Child Qualifies
Fill out the form below to help determine if you or your child may be eligible for the FLAIR Study.
Adults and children ages 4 and over, who have been diagnosed with asthma for at least 1 year and have had 1 or more asthma attacks requiring treatment in the past 12 months may qualify for the FLAIR Study. Adults over the age of 18 must not be current smokers or have a history of heavy smoking.
If you are under the age of 18, you may not directly enter any information, and your legal parent or guardian must enter this information on your behalf.
About Asthma
Asthma is one of the most common chronic diseases affecting people of all ages.
If a person has asthma, the airways in their lungs can become swollen (inflamed) and narrowed at times, causing breathing difficulties like wheezing and chest tightness.
There are certain factors that can set off or worsen asthma symptoms, such as pollen, exercise, viral infections, or cold air. These are called “asthma triggers.” When asthma symptoms get worse, it is called an asthma exacerbation or an “asthma attack.”
The FLAIR Study: What to Expect
The FLAIR Study is evaluating an investigational drug to see how it works in reducing the severity and frequency of asthma attacks in children and adults.
The investigational drug is a combination of 2 commercially approved drugs used separately to treat asthma, administered through a single inhaler. The investigational drug will be administered using an inhaler device. You or your child will have an equal chance of receiving the investigational drug in high or low dose, or receiving albuterol sulfate (ABS, also known as salbutamol), which is a common drug used for the rescue treatment of asthma.
Screening Period (approximately 2 weeks)
Participants will visit the research center for tests and assessments to check eligibility in order to take part in the FLAIR Study. Minors will need to be accompanied by a parent or guardian. The screening procedures, including taking a medical history, and a physical examination, may take place at 1 or more visits.
Run-In Period (approximately 2 to 4 weeks)
Participants will receive a rescue inhaler to use at home along with their usual asthma treatment. Participants will visit the center once for training on inhaler use and receive a diary to track symptoms and medication use. A home spirometer will also be provided for daily lung function checks.
Study Treatment Period (at least 24 weeks)
If eligible after the Run-In Period, participants will receive the study inhaler to use at home. During this period, they’ll visit the center every 3 months. In between research center visits, the study team will contact you by phone every month to ask how you or your child is feeling.
End of Study/End of Study Treatment Visit
These visits will be scheduled when the study is completed or if the participant stops the study treatment and leaves the study early.
Participation in the FLAIR Study is completely voluntary. If you or your child takes part in the study, you/they can end participation at any time and for any reason. If you/they decide not to participate, it will not affect your/their medical care now or in the future.
Common Questions
What is a clinical research study?
Clinical studies follow specific rules to protect the rights, safety, well-being, and confidentiality of study participants. The results help government regulators decide if a study drug is safe and should be made available to the public. Clinical studies are the only way to develop new medical treatments.
What is the investigational medication being researched in this study?
The FLAIR Study is evaluating an investigational drug to see how it works in reducing the severity and frequency of asthma attacks in children and adults. The investigational drug is a combination of 2 commercially approved drugs, fluticasone propionate and albuterol sulfate, used separately to treat asthma, administered through a single inhaler.
Are there costs or compensation involved in participating in this study?
How will participants be monitored during the FLAIR Study?
During the study, the study team will monitor each participant’s health. Laboratory tests (blood and urine), physical examinations, lung function tests, heart assessments, questionnaires, and other procedures will be conducted as part of the study. The study team will contact participants by phone every month to ask how they are feeling. Participants will also be asked to enter information about their asthma symptoms into an electronic diary twice daily, participants will also complete a breathing test (spirometry) each morning at home.
What are the rights as a participant and what will happen if they decide not to participate?
Participation in the FLAIR Study is completely voluntary.
If you or your child decides to take part in the study, you/they can end their participation at any time and for any reason. If you/they decide not to participate, it will not affect your/their medical care now or in the future.
Find a Research Center Near You
Current Research Centers working with pediatric, adolescent, and/or adult participants are listed below. Additional Research Centers may be added at any time.
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